T10P (p.Thr10Pro) variant of HBD (Hemoglobin subunit delta)
T10P (p.Thr10Pro) in HBD (Hemoglobin subunit delta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
T10P (p.Thr10Pro) variant details
- p.Thr10Pro
- gnomAD 11-5234406-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.57
- ESM-1b 1.00
- AlphaMissense 0.41
- MetaLR 0.50
- MetaSVM -0.49
- CADD 1.32
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available