P37S (p.Pro37Ser) variant of HBD (Hemoglobin subunit delta)
P37S (p.Pro37Ser) in HBD (Hemoglobin subunit delta) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
P37S (p.Pro37Ser) variant details
- p.Pro37Ser
- TOPMed rs1409273019
- gnomAD rs1409273019
- Missense
- Variant Prioritization Score for Impact Estimate 0.864
- REVEL 0.86
- ESM-1b 1.00
- AlphaMissense 0.95
- MetaLR 0.98
- MetaSVM 1.04
- CADD 25.10
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available