C63Y (p.Cys63Tyr) variant of HAVCR2 (Q8TDQ0)
C63Y (p.Cys63Tyr) in HAVCR2 (Q8TDQ0) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data.
C63Y (p.Cys63Tyr) variant details
- p.Cys63Tyr
- gnomAD rs1328023154
- Missense
- Variant Prioritization Score for Impact Estimate 0.613
- REVEL 0.50
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)