G121T (p.Gly121Thr) variant of GYS2 (P54840)
G121T (p.Gly121Thr) in GYS2 (P54840) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes structural context.
G121T (p.Gly121Thr) variant details
- p.Gly121Thr
- NCI-TCGA Cosmic COSV9967
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.28
- ESM-1b 0.00
- AlphaMissense 0.19
- MetaLR 0.47
- MetaSVM -0.24
- SIFT 0.17
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available