S25S (p.Ser25Ser) variant of GUCY2D (Retinal guanylyl cyclase 1)
S25S (p.Ser25Ser) in GUCY2D (Retinal guanylyl cyclase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
S25S (p.Ser25Ser) variant details
- p.Ser25Ser
- gnomAD 17-8003122-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.123
- CADD 5.93
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available