G15W (p.Gly15Trp) variant of GUCY2D (Retinal guanylyl cyclase 1)
G15W (p.Gly15Trp) in GUCY2D (Retinal guanylyl cyclase 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
G15W (p.Gly15Trp) variant details
- p.Gly15Trp
- gnomAD 17-8003090-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.36
- ESM-1b 0.00
- AlphaMissense 0.10
- CADD 11.40
- PolyPhen-2 0.19
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available