V8V (p.Val8Val) variant of GRN (Progranulin)
V8V (p.Val8Val) in GRN (Progranulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
V8V (p.Val8Val) variant details
- p.Val8Val
- rs1318632635
- gnomAD 17-44349188-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.218
- CADD 8.74
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available