T3T (p.Thr3Thr) variant of GRN (Progranulin)
T3T (p.Thr3Thr) in GRN (Progranulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
T3T (p.Thr3Thr) variant details
- p.Thr3Thr
- gnomAD 17-44349173-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.183
- CADD 5.36
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available