T11S (p.Thr11Ser) variant of GRN (Progranulin)
T11S (p.Thr11Ser) in GRN (Progranulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
T11S (p.Thr11Ser) variant details
- p.Thr11Ser
- gnomAD 17-44349195-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.09
- CADD 6.69
- PolyPhen-2 0.01
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available