S38G (p.Ser38Gly) variant of GRN (Progranulin)
S38G (p.Ser38Gly) in GRN (Progranulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
S38G (p.Ser38Gly) variant details
- p.Ser38Gly
- gnomAD 17-44349276-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0943
- REVEL 0.07
- CADD 7.32
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available
- Literature evidence available