R55R (p.Arg55Arg) variant of GRN (Progranulin)
R55R (p.Arg55Arg) in GRN (Progranulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
R55R (p.Arg55Arg) variant details
- p.Arg55Arg
- gnomAD 17-44349452-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.208
- CADD 8.96
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available