L46L (p.Leu46Leu) variant of GRN (Progranulin)

L46L (p.Leu46Leu) in GRN (Progranulin) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.

L46L (p.Leu46Leu) variant details