D33N (p.Asp33Asn) variant of GRN (Progranulin)
D33N (p.Asp33Asn) in GRN (Progranulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D33N (p.Asp33Asn) variant details
- p.Asp33Asn
- Ensembl rs1021941321
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.09
- CADD 21.00
- PolyPhen-2 0.02
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available