D22E (p.Asp22Glu) variant of GRN (Progranulin)
D22E (p.Asp22Glu) in GRN (Progranulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
D22E (p.Asp22Glu) variant details
- p.Asp22Glu
- gnomAD rs2048348383
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.37
- CADD 24.10
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available