D22D (p.Asp22Asp) variant of GRN (Progranulin)
D22D (p.Asp22Asp) in GRN (Progranulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
D22D (p.Asp22Asp) variant details
- p.Asp22Asp
- gnomAD 17-44349230-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.187
- CADD 12.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available