C61G (p.Cys61Gly) variant of GRN (Progranulin)
C61G (p.Cys61Gly) in GRN (Progranulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
C61G (p.Cys61Gly) variant details
- p.Cys61Gly
- gnomAD rs1291370551
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.56
- CADD 24.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available