C41C (p.Cys41Cys) variant of GRN (Progranulin)
C41C (p.Cys41Cys) in GRN (Progranulin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
C41C (p.Cys41Cys) variant details
- p.Cys41Cys
- rs1452920555
- gnomAD 17-44349287-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.287
- CADD 12.40
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available