V16D (p.Val16Asp) variant of GRM5 (P41594)
V16D (p.Val16Asp) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
V16D (p.Val16Asp) variant details
- p.Val16Asp
- cosmic curated COSV59606
- gnomAD rs1358659195
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.53
- MetaLR 0.57
- MetaSVM -0.03
- CADD 20.50
- PolyPhen-2 0.05
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)