V130M (p.Val130Met) variant of GRM5 (P41594)
V130M (p.Val130Met) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
V130M (p.Val130Met) variant details
- p.Val130Met
- ESP rs144706715
- ExAC rs144706715
- TOPMed rs144706715
- gnomAD rs144706715
- Missense
- Variant Prioritization Score for Impact Estimate 0.397
- REVEL 0.26
- MetaLR 0.42
- MetaSVM -0.29
- CADD 17.80
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)