T90I (p.Thr90Ile) variant of GRM5 (P41594)
T90I (p.Thr90Ile) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data.
T90I (p.Thr90Ile) variant details
- p.Thr90Ile
- TOPMed rs1003036477
- gnomAD rs1003036477
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.46
- MetaLR 0.57
- MetaSVM 0.26
- CADD 24.80
- PolyPhen-2 0.64
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)