S42P (p.Ser42Pro) variant of GRM5 (P41594)
S42P (p.Ser42Pro) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data.
S42P (p.Ser42Pro) variant details
- p.Ser42Pro
- cosmic curated COSV10055
- gnomAD rs1941673321
- Missense
- Variant Prioritization Score for Impact Estimate 0.614
- REVEL 0.66
- MetaLR 0.53
- MetaSVM 0.00
- CADD 24.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)