S23T (p.Ser23Thr) variant of GRM5 (P41594)
S23T (p.Ser23Thr) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data.
S23T (p.Ser23Thr) variant details
- p.Ser23Thr
- ExAC rs750584568
- TOPMed rs750584568
- gnomAD rs750584568
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.19
- MetaLR 0.57
- MetaSVM -0.39
- CADD 14.70
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)