S23N (p.Ser23Asn) variant of GRM5 (P41594)
S23N (p.Ser23Asn) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
S23N (p.Ser23Asn) variant details
- p.Ser23Asn
- ExAC rs750584568
- TOPMed rs750584568
- gnomAD rs750584568
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.18
- MetaLR 0.52
- MetaSVM -0.46
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)