S19G (p.Ser19Gly) variant of GRM5 (P41594)
S19G (p.Ser19Gly) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
S19G (p.Ser19Gly) variant details
- p.Ser19Gly
- cosmic curated COSV10518
- ExAC rs780067745
- gnomAD rs780067745
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.30
- MetaLR 0.75
- MetaSVM 0.63
- CADD 20.80
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)