S136P (p.Ser136Pro) variant of GRM5 (P41594)
S136P (p.Ser136Pro) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data.
S136P (p.Ser136Pro) variant details
- p.Ser136Pro
- ExAC rs754338771
- gnomAD rs754338771
- Missense
- Variant Prioritization Score for Impact Estimate 0.208
- REVEL 0.12
- MetaLR 0.17
- MetaSVM -0.94
- CADD 17.50
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)