S134F (p.Ser134Phe) variant of GRM5 (P41594)
S134F (p.Ser134Phe) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data.
S134F (p.Ser134Phe) variant details
- p.Ser134Phe
- cosmic curated COSV59602
- TOPMed rs1321899599
- gnomAD rs1321899599
- Missense
- Variant Prioritization Score for Impact Estimate 0.598
- REVEL 0.50
- MetaLR 0.72
- MetaSVM 0.09
- CADD 25.70
- PolyPhen-2 0.84
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)