S119Y (p.Ser119Tyr) variant of GRM5 (P41594)
S119Y (p.Ser119Tyr) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data.
S119Y (p.Ser119Tyr) variant details
- p.Ser119Tyr
- ExAC rs774109600
- TOPMed rs774109600
- gnomAD rs774109600
- Missense
- Variant Prioritization Score for Impact Estimate 0.794
- REVEL 0.80
- MetaLR 0.78
- MetaSVM 0.63
- CADD 26.90
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)