R61C (p.Arg61Cys) variant of GRM5 (P41594)
R61C (p.Arg61Cys) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data.
R61C (p.Arg61Cys) variant details
- p.Arg61Cys
- cosmic curated COSV59634
- gnomAD rs1429940712
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.51
- MetaLR 0.46
- MetaSVM -0.15
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)