R17H (p.Arg17His) variant of GRM5 (P41594)
R17H (p.Arg17His) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data.
R17H (p.Arg17His) variant details
- p.Arg17His
- 1000Genomes rs200406314
- ExAC rs200406314
- TOPMed rs200406314
- gnomAD rs200406314
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.24
- MetaLR 0.63
- MetaSVM -0.19
- CADD 20.70
- PolyPhen-2 0.10
- SIFT 0.56
- Most common in the 1KG:ACB population (allele frequency 0.0054)