R138H (p.Arg138His) variant of GRM5 (P41594)
R138H (p.Arg138His) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
R138H (p.Arg138His) variant details
- p.Arg138His
- cosmic curated COSV59609
- 1000Genomes rs569390300
- ExAC rs569390300
- TOPMed rs569390300
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.22
- MetaLR 0.38
- MetaSVM -0.30
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the 1KG:CDX population (allele frequency 0.0057)