Q108E (p.Gln108Glu) variant of GRM5 (P41594)
Q108E (p.Gln108Glu) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data.
Q108E (p.Gln108Glu) variant details
- p.Gln108Glu
- gnomAD rs1254238852
- Missense
- Variant Prioritization Score for Impact Estimate 0.628
- REVEL 0.58
- MetaLR 0.53
- MetaSVM 0.02
- CADD 25.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)