P87S (p.Pro87Ser) variant of GRM5 (P41594)
P87S (p.Pro87Ser) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data.
P87S (p.Pro87Ser) variant details
- p.Pro87Ser
- ExAC rs775471544
- TOPMed rs775471544
- gnomAD rs775471544
- Missense
- Variant Prioritization Score for Impact Estimate 0.779
- REVEL 0.83
- MetaLR 0.66
- MetaSVM 0.33
- CADD 26.10
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)