P32S (p.Pro32Ser) variant of GRM5 (P41594)
P32S (p.Pro32Ser) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data.
P32S (p.Pro32Ser) variant details
- p.Pro32Ser
- gnomAD rs200353980
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.36
- MetaLR 0.52
- MetaSVM -0.05
- CADD 20.70
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)