N80S (p.Asn80Ser) variant of GRM5 (P41594)
N80S (p.Asn80Ser) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data.
N80S (p.Asn80Ser) variant details
- p.Asn80Ser
- ExAC rs761478505
- gnomAD rs761478505
- Missense
- Variant Prioritization Score for Impact Estimate 0.828
- REVEL 0.93
- MetaLR 0.92
- MetaSVM 1.06
- CADD 25.30
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)