N80D (p.Asn80Asp) variant of GRM5 (P41594)
N80D (p.Asn80Asp) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data.
N80D (p.Asn80Asp) variant details
- p.Asn80Asp
- gnomAD rs1277050421
- Missense
- Variant Prioritization Score for Impact Estimate 0.829
- REVEL 0.92
- MetaLR 0.92
- MetaSVM 1.06
- CADD 26.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)