L76V (p.Leu76Val) variant of GRM5 (P41594)
L76V (p.Leu76Val) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data.
L76V (p.Leu76Val) variant details
- p.Leu76Val
- ExAC rs201710799
- TOPMed rs201710799
- gnomAD rs201710799
- Missense
- Variant Prioritization Score for Impact Estimate 0.598
- REVEL 0.58
- MetaLR 0.44
- MetaSVM -0.38
- CADD 19.00
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)