L126F (p.Leu126Phe) variant of GRM5 (P41594)
L126F (p.Leu126Phe) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
L126F (p.Leu126Phe) variant details
- p.Leu126Phe
- Ensembl rs1941666484
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.28
- MetaLR 0.29
- MetaSVM -0.69
- CADD 16.50
- PolyPhen-2 0.12
- SIFT 0.70
- Most common in the Middle Eastern population (allele frequency 0.00017)