K51E (p.Lys51Glu) variant of GRM5 (P41594)
K51E (p.Lys51Glu) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data.
K51E (p.Lys51Glu) variant details
- p.Lys51Glu
- ExAC rs199965117
- gnomAD rs199965117
- Missense
- Variant Prioritization Score for Impact Estimate 0.607
- REVEL 0.60
- MetaLR 0.63
- MetaSVM 0.20
- CADD 24.50
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)