K141R (p.Lys141Arg) variant of GRM5 (P41594)
K141R (p.Lys141Arg) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data.
K141R (p.Lys141Arg) variant details
- p.Lys141Arg
- Ensembl rs1295196167
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- REVEL 0.47
- MetaLR 0.72
- MetaSVM 0.45
- CADD 23.90
- PolyPhen-2 0.15
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)