I89V (p.Ile89Val) variant of GRM5 (P41594)
I89V (p.Ile89Val) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data.
I89V (p.Ile89Val) variant details
- p.Ile89Val
- ESP rs138949490
- gnomAD rs138949490
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.16
- MetaLR 0.21
- MetaSVM -0.85
- CADD 20.40
- PolyPhen-2 0.03
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 2.4e-05)