I36V (p.Ile36Val) variant of GRM5 (P41594)
I36V (p.Ile36Val) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data.
I36V (p.Ile36Val) variant details
- p.Ile36Val
- gnomAD rs1299864472
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.43
- MetaLR 0.67
- MetaSVM 0.29
- CADD 23.20
- PolyPhen-2 0.92
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)