I143V (p.Ile143Val) variant of GRM5 (P41594)
I143V (p.Ile143Val) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data.
I143V (p.Ile143Val) variant details
- p.Ile143Val
- gnomAD rs77734657
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- REVEL 0.39
- MetaLR 0.44
- MetaSVM -0.25
- CADD 23.50
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)