G125V (p.Gly125Val) variant of GRM5 (P41594)
G125V (p.Gly125Val) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data.
G125V (p.Gly125Val) variant details
- p.Gly125Val
- ExAC rs776573553
- TOPMed rs776573553
- gnomAD rs776573553
- Missense
- Variant Prioritization Score for Impact Estimate 0.698
- REVEL 0.60
- MetaLR 0.85
- MetaSVM 0.78
- CADD 24.30
- PolyPhen-2 0.67
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)