F137L (p.Phe137Leu) variant of GRM5 (P41594)
F137L (p.Phe137Leu) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data.
F137L (p.Phe137Leu) variant details
- p.Phe137Leu
- cosmic curated COSV10736
- ExAC rs267603230
- gnomAD rs267603230
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.21
- MetaLR 0.31
- MetaSVM -0.71
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 0.43
- Most common in the South Asian population (allele frequency 1.2e-05)