E14G (p.Glu14Gly) variant of GRM5 (P41594)
E14G (p.Glu14Gly) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
E14G (p.Glu14Gly) variant details
- p.Glu14Gly
- ExAC rs754913759
- gnomAD rs754913759
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.44
- MetaLR 0.69
- MetaSVM 0.38
- CADD 22.20
- PolyPhen-2 0.11
- SIFT 0.34
- Most common in the South Asian population (allele frequency 0.00016)