E124G (p.Glu124Gly) variant of GRM5 (P41594)
E124G (p.Glu124Gly) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data.
E124G (p.Glu124Gly) variant details
- p.Glu124Gly
- gnomAD rs1941666886
- Missense
- Variant Prioritization Score for Impact Estimate 0.531
- REVEL 0.51
- MetaLR 0.67
- MetaSVM 0.30
- CADD 23.30
- PolyPhen-2 0.42
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)