E121Q (p.Glu121Gln) variant of GRM5 (P41594)
E121Q (p.Glu121Gln) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data.
E121Q (p.Glu121Gln) variant details
- p.Glu121Gln
- ESP rs151133635
- ExAC rs151133635
- gnomAD rs151133635
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.52
- MetaLR 0.79
- MetaSVM 0.62
- CADD 24.80
- PolyPhen-2 0.96
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)