D115E (p.Asp115Glu) variant of GRM5 (P41594)
D115E (p.Asp115Glu) in GRM5 (P41594) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data.
D115E (p.Asp115Glu) variant details
- p.Asp115Glu
- 1000Genomes rs140113398
- ESP rs140113398
- ExAC rs140113398
- TOPMed rs140113398
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- REVEL 0.61
- MetaLR 0.61
- MetaSVM 0.06
- CADD 24.40
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.031)