R11L (p.Arg11Leu) variant of GRIN2D (O15399)
R11L (p.Arg11Leu) in GRIN2D (O15399) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
R11L (p.Arg11Leu) variant details
- p.Arg11Leu
- gnomAD 19-48398424-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.04
- ESM-1b 0.00
- AlphaMissense 0.16
- CADD 18.40
- PolyPhen-2 0.00
- SIFT 0.98
- Population evidence available
- Structural context available
- Literature evidence available