P7S (p.Pro7Ser) variant of GRIN2D (O15399)
P7S (p.Pro7Ser) in GRIN2D (O15399) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
P7S (p.Pro7Ser) variant details
- p.Pro7Ser
- gnomAD 19-48398411-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.10
- CADD 23.40
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.2e-06)
- Structural context available
- Literature evidence available